Recombinant vWF Monoclonal Antibody

Specifications

Catalog number

AN300105P-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

Abbreviation

VWF

UniProt

P04275

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human vWF protein

Target

Von Willebrand antigen; VWF; F8VWF; VWD; Coagulation factor VIII; Coagulation factor VIII VWF; Factor VIII related antigen; von Willebrand antigen 2; von Willebrand antigen II; Von Willebrand disease; Von Willebrand Factor

Clonality

Monoclonal

Clone

11G9

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Cardiovascular; Cancer; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG