Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody

Catalog number AN300111P

Price for AN300111P

Size / count 100 µL

Specifications

Catalog number: AN300111P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Leukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4) . This enzyme also has some peptidase activity. The leukotrienes (LTs) are a class of structurally related lipid mediators involved in the development and maintenance of inflammatory and allergic reactions. In the biosynthesis of LTs, arachidonic acid was converted into the unstable intermediate epoxide LTA4, which may, in turn, be conjugated with glutathione to form the spasmogenic LTC4, or hydrolyzed into the pro-inflammatory lipid mediator LTB4 in a reaction catalyzed by Leukotriene A4 hydrolase (LTA4H) . LTB4 is a classical chemoattractant of human neutrophils and triggers adherence and aggregation of leukocytes to vascular endothelium, and also modulates immune responses. As a bifunctional zinc metalloenzyme, LTA4H also exhibits an anion-dependant arginyl aminopeptidase activity of high efficiency and specificity in addition to its epoxide hydrolase activity. LTA4H is regarded as a therapeutic target for inflammation.
Abbreviation: LTA4H
UniProt: P09960
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human Leukotriene A4 Hydrolase / LTA4H protein
Target: LTA; LKHA; LTA4H; FLJ17564; Leukotriene A (4) hydrolase; Leukotriene A4 hydrolase; Leukotriene A-4 hydrolase; LKHA4; LTA4 hydrolase; LTA-4 hydrolase; LTA4
Clonality: Monoclonal
Clone: 12F7
Conjugation: Unconjugated
Applications: WB; ICC/IF; IP
Field of Research: Immunology; Cancer; Metabolism
Purification: Protein A
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; ICC/IF 1:100-1:500; IP 1-2 μL/mg of lysate
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 69 kDa
Observed Molecular Weight: 69 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody?

The catalog number for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is AN300111P.

What sizes are available for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody?

Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody in stock?

Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody?

Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody?

Estimated delivery time for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody?

The safety data sheet for Recombinant Leukotriene A4 Hydrolase/LTA4H Monoclonal Antibody is available here: https://789.bio/eb/OEYibvBj.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.