Recombinant Carbonic Anhydrase VB/CA5B Monoclonal Antibody

Specifications

Catalog number

AN300121P

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2005]

Abbreviation

CA5B

UniProt

Q9Y2D0

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Carbonic Anhydrase VB / CA5B protein

Target

CA5B; CA-VB; CA VB; Carbonate dehydratase VB; Carbonic anhydrase 5B; Carbonic Anhydrase 5B Mitochondrial; Carbonic anhydrase VB; mitochondrial; CAVB

Clonality

Monoclonal

Clone

9D11

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Tags & Cell Markers; Signal Transduction; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG