Recombinant EpCAM/TROP-1/TACSTD1 Monoclonal Antibody

Specifications

Catalog number

AN300200P-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Abbreviation

EpCAM

UniProt

P16422

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human EpCAM protein

Target

M4S; MIC; M1S; DIAR; TROP; HNPCC; GA733; TACSTD; EGP; EPCAM; DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1; Ep-CAM; epithelial cell adhesion molecule; GA733-2; M1S2; MK-1; KSA; EGP40; TROP1;17 1A;323/A3;35-KD glycoprotein; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; chromosome 4; CO 17A; CO17 1A; CO17A; EGP 2; EGP2; Ep CAM; EpCAM1; Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) ; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; Epithelial glycoprotein 1; Epithelial glycoprotein 314; EpithelialGlycoprotein; GA733 1; GA733 2; gastrointestinal tumor-associated antigen 2; gp4; hEGP 2; hEGP314; Human epithelial glycoprotein 2; KS 1/4 antigen; KS 1/4 antigen.KSA; Ly74; Lymphocyte antigen 74; M1S 1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component; Membrane component chromosome 4 surface marker (35kD glycoprotein) ; MK 1; Protein 289A; surface marker; surface marker 1; TACD1; Tumor associated calcium signal transducer 1; Tumor associated calcium signal transducer 2 precursor; Tumor-associated calcium signal transducer 1

Clonality

Monoclonal

Clone

8C2

Conjugation

Unconjugated

Applications

WB; IHC-P; FCM; ICC/IF; IP

Field of Research

Tags & Cell Markers

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; FCM 1:100-1:500; IHC-P 1:1000-1:5000; ICC/IF 1:250-1:5000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

40 kDa

Isotype

IgG