Recombinant GSTM2 Monoclonal Antibody

Specifications

Catalog number

AN300246P

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Abbreviation

GSTM2

UniProt

P28161

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human GSTM2 protein

Target

GST; GSTM2; GST4; GSTM; GSTM2-2; GTHMUS; Glutathione S alkyltransferase M2; Glutathione S aralkyltransferase M2; Glutathione S aryltransferase M2; Glutathione S transferase 4; Glutathione S transferase M1; Glutathione S transferase M2 (muscle) ; Glutathione S transferase Mu 2; Glutathione S transferase Mu 2 (muscle) ; glutathione S-transferase mu 2; glutathione S-transferase mu 2 (muscle) ; GST class mu 2; GST class-mu 2; GST muscle; MGC117303; S (hydroxyalkyl) glutathione lyase M2

Clonality

Monoclonal

Clone

6F5

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Signal Transduction; Metabolism; Tags & Cell Markers

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG