Recombinant SOD2 Monoclonal Antibody — image 1 of 2

Product details

Recombinant SOD2 Monoclonal Antibody

Catalog number AN300261P

Discontinued

Price for AN300261P

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: AN300261P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Superoxide Dismutases (SODs), originally identified as Indophenoloxidases (IPOs), are enzymes that catalyze the conversion of naturally-occuring but harmful superoxide radicals into molecular oxygen and hydrogen peroxide. Superoxide Dismutases 2 (SOD2), also known as Manganese (Mn) SOD, mitochondrial SOD, and IPO-B, is an intramitochondrial 22 kDa homotetramer. Each SOD2 monomer binds one Mn2+ ion. Three isozymes of SOD have been identified and are functionally related but have very modest sequence homology. SOD2 shares only 23% and 17% sequence identity with SOD1 and SOD3, respectively. SOD2 is, however, well conserved from species to species and shares 90% and 87% homology with mouse and rat SOD2, respectively. Oxidative stress has been implicated in many diseases and the chief source of reactive oxygen species within the cell is the mitochondrion. SOD2 is a free radical scavenging enzyme that protects against damage from superoxide produced as a byproduct of oxidative phosphorylation. SOD2 is required for normal biologic function of tissues by maintaining the integrity of mitochondrial enzymes susceptible to inactivation by superoxide. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.
Abbreviation: SOD2
UniProt: P04179
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human SOD2 protein
Target: SOD; MVCD; superoxide dismutase; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD; SOD2; Superoxide Dismutase [Mn] Mitochondrial; superoxide dismutase 2; IPOB; IPO-B; MNSOD; Mn-SOD; MVCD6; superoxide dismutase 2; EC:1.15.1.1; mitochondrial; Superoxide dismutase [Mn]
Clonality: Monoclonal
Clone: 012
Conjugation: Unconjugated
Applications: IHC-P
Field of Research: Cell Biology; Signal Transduction; Neuroscience; Cardiovascular; Cancer; Metabolism
Purification: Protein A
Concentration: 1 mg/mL
Dilution: IHC-P 1:100-1:500
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant SOD2 Monoclonal Antibody?

The catalog number for Recombinant SOD2 Monoclonal Antibody is AN300261P.

What sizes are available for Recombinant SOD2 Monoclonal Antibody?

Recombinant SOD2 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant SOD2 Monoclonal Antibody in stock?

Recombinant SOD2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant SOD2 Monoclonal Antibody?

Recombinant SOD2 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant SOD2 Monoclonal Antibody?

Estimated delivery time for Recombinant SOD2 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant SOD2 Monoclonal Antibody?

The safety data sheet for Recombinant SOD2 Monoclonal Antibody is available here: https://789.bio/eb/LeIMDp0m.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.