Recombinant Human IL17D Protein (Sumo Tag)

Specifications

Catalog number

PDEH100494-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL17D is a secreted cytokine with homology to the IL-17 family of proteins. IL17D is preferentially expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. The treatment of endothelial cells with IL17D has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by IL17D was found to be NF-kappa B-dependent.

Abbreviation

IL17D

Synonyms

IL 17D; IL 22; IL 27; IL-17D; IL-27; IL17D; IL17D; IL27; Interleukin 17D; Interleukin 27; Interleukin-17D; Interleukin-27

UniProt

Q8TAD2

Accession Number

Q8TAD2

Expression System

E.coli

Tag

N-Sumo

Sequence

Ala16-Pro202

Field of Research

Immunology; Cancer

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

33.4 kDa

Observed Molecular Weight

35-40 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human