Recombinant Human CCL23/MPIF-1 Protein (Sumo Tag)

Specifications

Catalog number

PDEH100607-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CCL23/MPIF-1, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23/MPIF-1 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23/MPIF-1 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

Abbreviation

CCL23/MPIF-1

Synonyms

CCL; CKB; SCYA; C-C Motif Chemokine; C C motif chemokine ligand; Small-Inducible Cytokine A; Macrophage Inflammatory Protein; Myeloid Progenitor Inhibitory Factor; C C motif chemokine ligand 23; C6 beta chemokine; C-C Motif Chemokine 23; CKB-8; CK-Beta-8; Macrophage Inflammatory Protein 3; MIP-3; MPIF-1; Myeloid Progenitor Inhibitory Factor 1; Small-Inducible Cytokine A23; MIP3; MPIF1; SCYA23; CCL23; Ckb-8; MIP-3; MPIF-1; SCYA23; CCL 23; CCL23 (30-99) ; Chemokine (C C motif) ligand 23; Chemokine CC motif ligand 23; ck beta 8; CKB 8; CKb8; Ckb-8-1; Hmrp-2a; member 23; MIP 3; MPIF 1; OTTHUMP00000163948; SCYA 23; Small inducible cytokine A 23; Small inducible cytokine subfamily A; Small inducible cytokine subfamily A (Cys-Cys)

UniProt

P55773

Accession Number

P55773

Expression System

E.coli

Tag

N-Sumo

Sequence

Arg22-Asn120

Field of Research

Immunology; Signal Transduction; Kits; Lysates; Other

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

23.8 kDa

Observed Molecular Weight

30 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human