Recombinant Mouse CCL6/C10 Protein (Trx Tag)

Specifications

Catalog number

PDEM100152-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

In mice , CCL6/C10 is expressed in cells from neutrophil and macrophage lineages , and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3 , and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However , in activated T cell lines , expression of CCL6/C10 is greatly reduced.CCL6/C10 can also be induced in the Mouse lung by the cytokine interleukin 13

Abbreviation

CCL6/C10

Synonyms

Scya; Chemokine C C motif Ligand; Small Inducible Cytokine A; chemokine (C-C motif) ligand; CCL 6; chemokine (C-C motif) ligand 6; Chemokine C C motif Ligand 6; MRP1; MRP-1; Small Inducible Cytokine A6; C10; Scya6; Ccl6; C10; CCL 6; chemokine (C-C motif) ligand 6; Chemokine C C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6

UniProt

P27784

Accession Number

P27784

Expression System

E.coli

Tag

N-Trx

Sequence

Gly22-Ala116

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

30.3 kDa

Observed Molecular Weight

32 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Mouse