Recombinant Human Fetuin B Protein (Fc Tag)

Specifications

Catalog number

PDMH100300-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fetuin-B , also known as Fetuin-like protein IRL685 and FETUB , is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family , part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions , including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in Human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level , notably including variations with respect to the archetypal fetuin-specific signature.

Abbreviation

Fetuin B

Synonyms

16G; IRL;16G2;2310011O17Rik; AI255764; D17980; Fet; Fetuin beta; Fetuin-B; Fetuin-like protein; Fetuin-like protein IRL685; Gugu; IRL685; Pp63; FETUB

UniProt

Q9UGM5

Accession Number

Q9UGM5

Expression System

Mammalian

Tag

C-Fc

Sequence

Cys16-Pro382

Field of Research

Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

65.3 kDa

Observed Molecular Weight

75-80 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human