Recombinant Mouse LBP Protein (His tag)

Specifications

Catalog number

PDMM100043-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with an LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.

Abbreviation

Lbp

Synonyms

BPI fold containing family D; member 2; Bpifd2; LBP; LBP; LBP1; Lipopolysaccharide binding protein; Lipopolysaccharide-binding protein; LPS binding protein; Ly88; MGC22233; OTTHUMP00000030965; RP23-407H16.4

UniProt

Q61805

Accession Number

Q61805

Expression System

Mammalian

Tag

C-His

Sequence

Met1-Val481

Field of Research

Immunology; Microbiology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.8 kDa

Observed Molecular Weight

58-60 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Mouse