Recombinant Human PF4 protein (GST tag)

Specifications

Catalog number

PDEH100773-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

Abbreviation

PF4

Synonyms

C-X-C motif chemokine 4; Endothelial cell growth inhibitor; Iroplact; Oncostatin-A; PF-4

UniProt

P02776

Accession Number

P02776

Expression System

E.coli

Tag

N-GST

Sequence

Glu32-Ser101

Field of Research

Immunology, Cardiovascular

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

33.7 kDa

Observed Molecular Weight

34 kDa

Species

Human