Recombinant Human IL-8 protein (GST tag)

Specifications

Catalog number

PDEH100775-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8 (6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8 (5-77) has increased activity on neutrophil activation and IL-8 (7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8 (1-77), respectively.

Abbreviation

IL-8

Synonyms

CXCL; Interleukin; C-X-C motif chemokine; Chemokine (C-X-C motif) ligand; IL8/CXCL; GCP; NAP; CXCL8; GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1;3-10C; AMCF-I; IL8/CXCL8; K60; Interleukin-8; IL-8; Emoctakin; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Granulocyte chemotactic protein 1 (GCP-1) ; Monocyte-derived neutrophil chemotactic factor (MDNCF) ; (Ala-IL-8) 77; (Ser-IL-8) 72;9E3; Beta thromboglobulin like protein; CEF-4; chemokine; CXC motif; GCP/IL-8 protein I; GCP/IL-8 protein II; GCP/IL-8 protein III; GCP/IL-8 protein IV; GCP/IL-8 protein V; GCP/IL-8 protein VI; Granulocyte chemotactic protein 1; IL-8 (1-77) ; IL-8 (9-77) ; IL8/NAP1 form I; IL8/NAP1 form II; IL8/NAP1 form III; IL8/NAP1 form IV; IL8/NAP1 form V; IL8/NAP1 form VI; Inteleukin 8; ligand 8; Lymphocyte-derived neutrophil-activating factor; MDNCF-b; MDNCF-c; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil activating peptide 1; Neutrophil activating protein 1; Neutrophil-activating factor; Neutrophil-activating protein 1; Protein 3 10C; Protein 3-10C; SCYB8; Small inducible cytokine subfamily B member 8; T cell chemotactic factor; T-cell chemotactic factor; TSG1

UniProt

P10145

Accession Number

P10145

Expression System

E.coli

Tag

N-GST

Sequence

Ser28-Ser99

Field of Research

Cardiovascular, Immunology, Cancer

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 85% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

34.3 kDa

Observed Molecular Weight

9 kDa & 35 kDa

Species

Human