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Product details

Recombinant Human MASP1 protein (His tag)

Catalog number PDEH100826-01

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Price for PDEH100826-01

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Size / count 20 µg

Specifications

Catalog number
PDEH100826-01
Size / count
20 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
Abbreviation
MASP1
Synonyms
CRARF; CRARF1; Complement Factor MASP-3; MASP-1; MASP1; Mannan-Binding Lectin Serine Protease 1; Mannose-Binding Lectin-Associated Serine Protease 1; PRSS5; RaRF; Serine Protease 5
UniProt
P48740
Accession Number
P48740
Expression System
E.coli
Tag
N-His
Sequence
His 20-Ala 447
Field of Research
Immunology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
47.0 kDa
Observed Molecular Weight
48 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human MASP1 protein (His tag)?

The catalog number for Recombinant Human MASP1 protein (His tag) is PDEH100826.

What sizes are available for Recombinant Human MASP1 protein (His tag)?

Recombinant Human MASP1 protein (His tag) is available in the following size(s): 20 µg, 100 µg, 500 µg, 1 mg.

How many pack sizes does Recombinant Human MASP1 protein (His tag) come in?

Recombinant Human MASP1 protein (His tag) is available in 4 different pack sizes.

Is Recombinant Human MASP1 protein (His tag) in stock?

Recombinant Human MASP1 protein (His tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human MASP1 protein (His tag)?

Recombinant Human MASP1 protein (His tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human MASP1 protein (His tag)?

Estimated delivery time for Recombinant Human MASP1 protein (His tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human MASP1 protein (His tag)?

The safety data sheet for Recombinant Human MASP1 protein (His tag) is available here: https://789.bio/eb/K8xaiH.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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