Recombinant Human AQP-3 protein (GST tag)

Specifications

Catalog number

PDEH100837-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Water channel required to promote glycerol permeability and water transport across cell membranes.Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.

Abbreviation

AQP-3

Synonyms

AQP 3; AQP-3; AQP3; Aqp3; Aquaglyceroporin-3; Aquaporin 3; Aquaporin-3; Aquaporin3; GIL; Gill blood group

UniProt

Q92482

Accession Number

Q92482

Expression System

E.coli

Tag

N-GST

Sequence

Leu 110-Ser 170

Field of Research

Cancer; Metabolism; Signal transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

31.6 kDa

Observed Molecular Weight

37 kDa

Species

Human