Recombinant Human Kallikrein 6/KLK6 Protein (His tag)

Specifications

Catalog number

PDEH100956-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members . The genes of this family aligned in tandem on chromosome 19q13.4 represent the largest contiguous group of proteases within the human genome. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung (2, 3) . Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes.

Abbreviation

Kallikrein 6; KLK6

Synonyms

KLK6; Kallikrein-6; Neurosin; PRSS18; PRSS9; Protease M; SP59; Serine Protease 18; Serine Protease 9

UniProt

Q92876

Accession Number

Q92876

Expression System

E.coli

Tag

N-His

Sequence

Glu 81-Lys 244

Field of Research

Cancer; Cell Biology; Neuroscience; signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.8 kDa

Observed Molecular Weight

20 kDa

Species

Human