Recombinant Human COMP protein (GST, His tag) — image 1 of 2

Product details

Recombinant Human COMP protein (GST, His tag)

Q: How do I request a quotation for this product?

Add the product and required quantity to your cart, then submit the quotation request from the checkout page. Include your contact and delivery details so the Afraxis team can respond.

Q: How can I identify the product or variant I need?

Check the product description, specifications and catalogue number on this page. If the product has multiple variants, select the required catalogue number and size before adding it to your cart.

Q: Where can I find product documentation?

Available product documents are listed in the Product documents section on this page. If a document you need is not listed, contact Afraxis and include the product name and catalogue number.

Q: How do I check the price and availability?

The product page shows the available variant and any displayed price information. For a quotation or confirmation for your order, add the product to your cart and submit a request.

Q: How long will delivery take?

Delivery timing depends on the product, supplier and destination. Request a quotation with your delivery details to confirm the expected timing for your order.

Q: Does this product require special handling or shipping?

Review any product-specific handling details shown on this page. If you are unsure about storage or shipping requirements, contact Afraxis with the product name and catalogue number.

Q: Who can use Afraxis products?

Afraxis products are supplied for laboratory and research use. Review the product documentation and intended-use information before use.

Q: How do I contact Afraxis about this product?

Use the contact form or contact details on the Afraxis website. Include the product name and catalogue number so the team can assist with your enquiry.

Catalog number PDEH101069-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for PDEH101069-01

Size / count 20 µg

Specifications

Catalog number: PDEH101069-01
Size / count: 20 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas.
Abbreviation: COMP
Synonyms: EDM1; EPD1; MED; PSACH; THBS5
UniProt: P49747
Accession Number: P49747
Expression System: E.coli
Tag: N-GST & C-His
Sequence: Gly 22-His 240
Field of Research: Signal Transduction; Cell biology; Stem cells
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Purity: > 95% as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 49.0 kDa
Observed Molecular Weight: 50 kDa
Species: Human

Product documents

Supporting information for this product.

Product Datasheet

Frequently Asked Questions

How do I request a quotation for this product?

Add the product and required quantity to your cart, then submit the quotation request from the checkout page. Include your contact and delivery details so the Afraxis team can respond.

How can I identify the product or variant I need?

Check the product description, specifications and catalogue number on this page. If the product has multiple variants, select the required catalogue number and size before adding it to your cart.

Where can I find product documentation?

Available product documents are listed in the Product documents section on this page. If a document you need is not listed, contact Afraxis and include the product name and catalogue number.

How do I check the price and availability?

The product page shows the available variant and any displayed price information. For a quotation or confirmation for your order, add the product to your cart and submit a request.

How long will delivery take?

Delivery timing depends on the product, supplier and destination. Request a quotation with your delivery details to confirm the expected timing for your order.

Does this product require special handling or shipping?

Review any product-specific handling details shown on this page. If you are unsure about storage or shipping requirements, contact Afraxis with the product name and catalogue number.

Who can use Afraxis products?

Afraxis products are supplied for laboratory and research use. Review the product documentation and intended-use information before use.

How do I contact Afraxis about this product?

Use the contact form or contact details on the Afraxis website. Include the product name and catalogue number so the team can assist with your enquiry.