Recombinant Mouse HSP-70/HSPA9 protein (His tag)

Specifications

Catalog number

PDEM100248-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU.Regulates erythropoiesis via stabilization of ISC assembly.May play a role in the control of cell proliferation and cellular aging.

Abbreviation

HSP-70; HSPA9

Synonyms

75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; MOT; Mortalin; PBP74; Peptide-binding protein 74

UniProt

P38647

Accession Number

P38647

Expression System

E.coli

Tag

N-His

Sequence

Glu 542-Gln 679

Field of Research

Cancer; Metabolism; Neuroscience; Sgnal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.1 kDa

Observed Molecular Weight

20 kDa

Species

Mouse