Recombinant Mouse HP protein (His tag)

Specifications

Catalog number

PDEM100255-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Haptoglobin is a 406 aminoacids (aa) protein that in humans is encoded by the HP gene. This gene encodes a preproprotein that is processed into alpha (aa 19-160) and beta (aa 162-406) chains that combine as a tetramer to produce haptoglobin. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.

Abbreviation

HP

Synonyms

HP; BP; HPA1S; Haptoglobin; Hp

UniProt

Q61646

Accession Number

Q61646

Expression System

E.coli

Tag

N-His

Sequence

Ala 118-Cys 281

Field of Research

Cancer; Cardiovascular

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

17.9 kDa

Observed Molecular Weight

22 kDa

Species

Mouse