Recombinant Rat KLK6 Protein (His Tag)

Specifications

Catalog number

PDER100152-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Abbreviation

KLK6

Synonyms

Bssp; KLK 6; KLK6; KLK9; Kallikrein 6 precursor; Kallikrein related peptidase 6; Kallikrein-6; Kallikrein6; Klk29; Klk6; Klk7; MGC9355; MSP; Neurosin; PRSS 18; PRSS 9; PRSS18; PRSS9; Protease M; Protease serine 18; Protease serine 9; Serine prote; hK 6; hK6; mGK 1; mGK1

UniProt

P36374

Accession Number

P36374-1

Expression System

E.coli

Tag

N-His

Sequence

Ile25-Pro261

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 80% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

26.3 kDa

Observed Molecular Weight

28.62 kDa

Species

Rat