Recombinant Rat ADP protein (His tag)

Specifications

Catalog number

PDER100179-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving insulin sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.

Abbreviation

ADP

Synonyms

ACDC; ACRP30; ADIPO; ADIPQTL1; ADPN; APM 1; APM1; Adipocyte; apM-1

UniProt

Q8K3R4

Accession Number

Q8K3R4

Expression System

E.coli

Tag

N-His

Sequence

Ile 19-Asn 244

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal TransductionStem Cells

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

24.8 kDa

Observed Molecular Weight

30 kDa

Species

Rat