Recombinant Rat GSTM2 protein (His tag)

Specifications

Catalog number

PDER100223-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one&nbsp, GST C-terminal domain and one&nbsp, GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.&nbsp, Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Abbreviation

GSTM2

Synonyms

GST4; GSTM; GSTM2-2; GTHMUS

UniProt

P08010

Accession Number

P08010

Expression System

E.coli

Tag

N-His

Sequence

Pro 2-Lys 218

Field of Research

Signal Transduction; Tags& Cell Markers; Cancer; metabolism

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

23.8 kDa

Observed Molecular Weight

30 kDa

Species

Rat