Recombinant Human IL-12 (p70) protein (His tag)

Specifications

Catalog number

PDMH100376-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Abbreviation

IL-12

Synonyms

NKSF; IL-12/IL-35 p; IL-12 subunit p; Interleukin 12/P; NK cell stimulatory factor chain; CLMF p; P35; CLMF; NFSK; NKSF1; IL-12A; CLMF p35; CLMF1; Cytotoxic Lymphocyte Maturation Factor 35 kDa; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12/IL-35 p35; Interleukin-12 subunit alpha; NK cell stimulatory factor chain 1; IL12A; IL12B; Interleukin 12/P70; CLMF; IL-12A; NFSK; NKSF1

UniProt

P29459

Accession Number

P29459

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Ser219

Field of Research

Immunology, Cancer

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 85% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.8 kDa

Observed Molecular Weight

38 kDa

Species

Human