Recombinant Human CXCL10 Protein (His Tag)

Specifications

Catalog number

PDEH100461-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.

Abbreviation

CXCL10

Synonyms

Interferon gamma-induced protein 10; IP-10; SCYB10; C7

UniProt

P02778

Accession Number

P02778

Expression System

E.coli

Tag

N-His

Sequence

Val22-Pro98

Field of Research

Immunology; Cancer; Microbiology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

8.5 kDa

Observed Molecular Weight

13 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human