Recombinant Human TNFRSF12A Protein (Sumo Tag)

Specifications

Catalog number

PDEH101139-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Abbreviation

TNFRSF12A

Synonyms

Fibroblast growth factor-inducible 14; FN14; TWEAK receptor

UniProt

Q9NP84

Accession Number

Q9NP84

Expression System

E.coli

Tag

N-Sumo

Sequence

Glu28-Pro80

Field of Research

Cancer; Immunology; Signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

18.7 kDa

Observed Molecular Weight

21 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human