Recombinant Mouse KIM-1 Protein (Halo Tag)

Specifications

Catalog number

PDMM100247-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa) . It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.

Abbreviation

KIM-1

Synonyms

HAVCR1; TIM-1; T-cell immunoglobulin and mucin domain 1

UniProt

Q5QNS5

Accession Number

Q5QNS5

Expression System

Mammalian

Tag

C-Halo

Sequence

Tyr22-Thr212

Field of Research

Cell Biology; Metabolism; Cardiovascular

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

54 kDa

Observed Molecular Weight

60-65 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Mouse