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Product details

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56]

Catalog number HA722849

Price for HA722849

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Size / count 100 µL

About this product

Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca2+ levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

Catalog number
HA722849
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Calcium dependent phospholipid binding protein antibody CPLA 2 antibody cPLA2 alpha antibody cPLA2 antibody Cytosolic phospholipase A2 antibody Cytosolic phospholipase A2 group IVA antibody Lysophospholipase antibody MGC126350 antibody PA24A_HUMAN antibody Phosphatidylcholine 2 acylhydrolase antibody Phosphatidylcholine 2-acylhydrolase antibody Phospholipase A2 group 4 A antibody Phospholipase A2 group IVA (cytosolic calcium dependent) antibody Phospholipase A2 group IVA antibody PhospholipaseA2 antibody PLA2G4 antibody pla2g4a antibody
Abbreviation
PLA2G4A, CPLA2, PLA2G4
Swiss Prot
P47712 Human, P47713 Mouse
Cellular Locus
Cytoplasm, Golgi apparatus membrane, Nucleus envelope.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser505 of human cPLA2 aa 491-540.
Isotype
IgG
Clone
PSH07-56
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, Dot Blot
Positive Control
HeLa cell lysate, RAW264.7 cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;Dot Blot: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 85 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56]?

The catalog number for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56] is HA722849.

What sizes are available for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56]?

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56] is available in the following size(s): 100 µL.

Is Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56] in stock?

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-56] used for?

Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosa

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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