PINK1 Rabbit Polyclonal Antibody — image 1 of 6

Product details

PINK1 Rabbit Polyclonal Antibody

Catalog number ER1706-27

Discontinued

Price for ER1706-27

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

A member of the serine / threonine protein kinase family, PTEN induced putative kinase 1 (PINK1) is a tumor suppressor. PINK1 is primarily located in mitochondria, and is ubiquitously expressed in testis, skeletal muscle, and heart tissue. at lower levels in pancreas, ovary, brain, placenta, kidney, liver, prostate and small intestine. During cellular stress PINK1 protects against mitochondrial dysfunction by inducing phosphorylation mitochondrial proteins. PINK1 mutations may give rise to different autophosphorylation activity. Mutations in the PINK1 gene (PARK6) are associated with early onset Parkinson's disease, a recessive neurodegenerative disorder characterized by resting tremor, muscular rigidity, bradykinesia and postural instability. Parkinson's disease generally involves the presence of intraneuronal accumulations of aggregated proteins (Lewy bodies) in brain neurons.

Specifications

Catalog number: ER1706-27
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9007-83-4
Product Name Alternative: BRPK antibody FLJ27236 antibody mitochondrial antibody PARK 6 antibody PARK6 antibody Phosphatase and Tensin Homolog antibody PINK 1 antibody PINK1 antibody PINK1_HUMAN antibody Protein kinase BRPK antibody PTEN induced putative kinase 1 antibody PTEN induced putative kinase protein 1 antibody PTEN-induced putative kinase protein 1 antibody Serine/threonine kinase PINK1 mitochondrial antibody Serine/threonine protein kinase PINK1 mitochondrial antibody Serine/threonine-protein kinase PINK1 antibody
Abbreviation: PINK1
Swiss Prot: Q9BXM7 Human
Cellular Locus: Mitochondrion outer membrane, Mitochondrion inner membrane, Cytoplasm, cytosol.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human PINK1 aa 94-581 / 581.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: HeLa treated with 10μM CCCP for 24 hours cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 63 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PINK1 Rabbit Polyclonal Antibody?

The catalog number for PINK1 Rabbit Polyclonal Antibody is ER1706-27.

Is PINK1 Rabbit Polyclonal Antibody in stock?

PINK1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PINK1 Rabbit Polyclonal Antibody used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.