APC Conjugated Human CD4 Recombinant Mouse Monoclonal Antibody [PSH04-93]

About this product

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene. CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T-helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, for example in untreated HIV infection, or following immune suppression prior to a transplant, the body is left vulnerable to a wide range of infections that it would otherwise have been able to fight.

Specifications

Catalog number

HA600121F

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CD 4 antibody CD4 (L3T4) antibody CD4 antibody CD4 antigen (p55) antibody CD4 antigen antibody CD4 molecule antibody CD4 receptor antibody CD4+ Lymphocyte deficiency, included antibody CD4_HUMAN antibody CD4mut antibody L3T4 antibody Leu3 antibody Ly-4 antibody Lymphocyte antigen CD4 antibody MGC165891 antibody OTTHUMP00000238897 antibody p55 antibody T cell antigen T4 antibody T cell antigen T4/LEU3 antibody T cell differentiation antigen L3T4 antibody T cell OKT4 deficiency, included antibody T cell surface antigen T4/Leu 3 antibody T cell surface antigen T4/Leu3 antibody T cell surface glycoprotein CD4 antibody T-cell surface antigen T4/Leu-3 antibody T-cell surface glycoprotein CD4 antibody W3/25 antibody W3/25 antigen antibody

Abbreviation

CD4

Swiss Prot

P01730 Human

Cellular Locus

Cell membrane.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within

Isotype

IgG1

Clone

PSH04-93

Conjugation

APC

Type

Recombinant Mouse monoclonal Antibody

Applications

FC

Positive Control

Human peripheral blood lymphocytes.

Dilution

FC: 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.

Molecular Weight

Predicted band size: 51 kDa

Storage Conditions

Store at 2°C to 8°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes