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Product details

LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28]

Catalog number HA721992

Price for HA721992

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Size / count 100 µL

About this product

Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It's a member of T cell factor/lymphoid enhancer factor (TCF/LEF) family. Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1). LEF1 is highly overexpressed and associated with disease progression and poor prognosis in B-cell chronic lymphocytic leukemia and other kinds of malignancies like colorectal cancer. It is also a promising potential drug target.

Specifications

Catalog number
HA721992
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DKFZp586H0919 antibody FLJ46390 antibody LEF 1 antibody LEF-1 antibody Lef1 antibody LEF1_HUMAN antibody Lymphoid enhancer binding factor 1 antibody Lymphoid enhancer-binding factor 1 antibody T cell specific transcription factor 1 alpha antibody T cell-specific transcription factor 1-alpha antibody TCF 1 alpha antibody TCF1 alpha antibody TCF1-alpha antibody TCF10 antibody TCF1alpha antibody TCF7L3 antibody Transcription factor T cell specific 1 alpha antibody
Abbreviation
LEF1
Swiss Prot
Q9UJU2 Human, P27782 Mouse, Q9QXN1 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human LEF1 aa 121-170 / 399.
Isotype
IgG
Clone
JE52-28
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Jurkat cell lysate, mouse thymus tissue lysate, rat thymus tissue lysate, Jurkat, human lymph node tissue, human thymus tissue, human tonsil tissue, rat thymus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:500 ;IHC-P: 1:500-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28]?

The catalog number for LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28] is HA721992.

What sizes are available for LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28]?

LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28] is available in the following size(s): 100 µL.

Is LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28] in stock?

LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28] used for?

Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It's a member of T cell factor/lymphoid enhancer factor (TCF/LEF) family. Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a func

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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