FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25]

Catalog number HA721642

Price for HA721642

Size / count 100 µL

About this product

Fibroblast growth factor 18 is a protein that in humans is encoded by the FGF18 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. FGF18 signals through fibroblast growth factor receptor FGFR3 to promote chondrogenesis and has been shown to cause thickening of cartilage in a murine model of osteoarthritis, and the recombinant version of it (sprifermin) is in clinical trial as a potential treatment for osteoarthritis. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Specifications

Catalog number: HA721642
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: FGF 18 antibody FGF-18 antibody Fgf18 antibody FGF18_HUMAN antibody FGFI antibody Fibroblast growth factor 18 antibody zFGF5 antibody
Abbreviation: Fgf18
Swiss Prot: O89101 Mouse
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Mouse
Immunogen: Recombinant protein within mouse FGF18 aa 1-207 / 207.
Isotype: IgG
Clone: PSH01-25
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 24 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25]?

The catalog number for FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25] is HA721642.

What sizes are available for FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25]?

FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25] is available in the following size(s): 100 µL.

Is FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25] in stock?

FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FGF18 Recombinant Rabbit Monoclonal Antibody [PSH01-25] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.