- Catalog number
- AN200175P
- Size / count
- 100 µL
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Background
- This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Abbreviation
- FCGR3A
- UniProt
- P08637
- Host
- Mouse
- Reactivity
- Human
- Immunogen
- Recombinant Human CD16a/FCGR3A protein
- Target
- FCR; IMD; FCG; Fcgr; IGFR; IgG Fc Receptor III; CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20; FCGR3A; CD16a Antigen; Fc-Gamma RIII; Fc-gamma RIIIa; Fc-Gamma RIII-Alpha; IgG Fc Receptor III-2; Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A; Fc&gamma-RIIIA-A; CD16a; CD 16; CD 16a; CD16B; CD16b antigen; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG low affinity IIIa receptor (CD16) ; Fc fragment of IgG receptor IIIa; Fc gamma R3; Fc gamma receptor III 2 (CD 16) ; Fc gamma receptor III A; Fc gamma receptor IIIA; Fc gamma receptor IIIb (CD 16) ; Fc gamma RIII; Fc gamma RIII alpha; Fc gamma RIII beta; Fc gamma RIIIa; Fc gamma RIIIb; Fc of IgG; FCG 3; FCG3A; Fc-gamma receptor III2 (CD 16) ; Fc-gamma receptor III2 (CD16) ; Fc-gamma receptor IIIb (CD16) ; FCgammaRIIIA; FCGR 3; FCGR 3A; FCGR3A protein; FCGRIII-2; FcR 10; FcR10; IGFR 3; IgG Fc receptor III 1; IgG Fc receptor III 2; immunoglobulin G Fc receptor III; immunoglobulin G Fc receptor III-2; low affinity III; low affinity IIIa; Low affinity IIIa receptor; low affinity IIIb; Low affinity immunoglobulin gamma Fc region receptor III A; Low affinity immunoglobulin gamma Fc region receptor IIIB; neutrophil-specific antigen NA; receptor (CD16) ; receptor (CD16a) ; receptor (CD16b) ; receptor for; receptor for (CD16)
- Clonality
- Monoclonal
- Clone
- 1F14
- Conjugation
- Unconjugated
- Applications
- IHC-P
- Field of Research
- Immunology; Stem Cells
- Purification
- Protein A
- Concentration
- 1 mg/mL
- Dilution
- IHC-P 1:250-1:1000
- Buffer
- 0.2 μm filtered solution in PBS
- Shipping Conditions
- Ice bag
- Storage Conditions
- This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
- Isotype
- IgG1
