Cytokeratin 8 Monoclonal Antibody — image 1 of 3

Product details

Cytokeratin 8 Monoclonal Antibody

Catalog number AN200190P

Price for AN200190P

Size / count 100 µL

Specifications

Catalog number: AN200190P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: KRT8 (Keratin 8) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. KRT8 is the major component of the intermediate filament cytoskeleton and is predominantly expressed in simple epithelial tissues. Aberrant expression of KRT8 is associated with multiple tumor progression and metastasis.KRT8 overexpression in renal cancer cell lines promoted cell migration and invasion. In contrast, KRT8 knockdown suppressed ccRCC metastasis both in vitro and in vivo.KRT8 expression may therefore be a biomarker or potential therapeutic target to identify patients with worse survival. Diseases associated with KRT8 include Liver Cirrhosis and Cryptogenic Cirrhosis.
Abbreviation: KRT8
UniProt: P05787
Host: Mouse
Reactivity: Human
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human Cytokeratin 8
Target: CYK; KRT; CYK8; KRT8; CARD2; CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; K2C8; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin; type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8; CK 8; CK8; CK-8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; Keratin; Keratin 8; Keratin type II cytoskeletal 8; Keratin-8; Krt 2.8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; type II cytoskeletal 8; Type-II keratin Kb8
Clonality: Monoclonal
Clone: 10F13
Conjugation: Unconjugated
Applications: IHC-P; ICC/IF
Field of Research: Signal Transduction; Cancer
Purification: Protein A
Concentration: 1 mg/mL
Dilution: IHC-P 1:500-1:5000; ICC/IF 1:20-1:100
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype: IgG1

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 Monoclonal Antibody?

The catalog number for Cytokeratin 8 Monoclonal Antibody is AN200190P.

What sizes are available for Cytokeratin 8 Monoclonal Antibody?

Cytokeratin 8 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Cytokeratin 8 Monoclonal Antibody in stock?

Cytokeratin 8 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8 Monoclonal Antibody?

Cytokeratin 8 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Cytokeratin 8 Monoclonal Antibody?

Estimated delivery time for Cytokeratin 8 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8 Monoclonal Antibody?

The safety data sheet for Cytokeratin 8 Monoclonal Antibody is available here: https://789.bio/eb/MqJFfjpc.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.