Recombinant PTP1B/PTPN1 Monoclonal Antibody

Catalog number AN300317P

Discontinued

Price for AN300317P

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: AN300317P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation: PTPN1
UniProt: P18031
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human PTP1B/PTPN1 protein
Target: PTPN; PTPN1; PTP1B
Clonality: Monoclonal
Clone: 8D4
Conjugation: Unconjugated
Applications: WB; IP
Field of Research: Signal Transduction; Cardiovascular
Purification: Protein A
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IP 1-4 μL/mg of lysate
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 50 kDa
Observed Molecular Weight: 50 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant PTP1B/PTPN1 Monoclonal Antibody?

The catalog number for Recombinant PTP1B/PTPN1 Monoclonal Antibody is AN300317P.

What sizes are available for Recombinant PTP1B/PTPN1 Monoclonal Antibody?

Recombinant PTP1B/PTPN1 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant PTP1B/PTPN1 Monoclonal Antibody in stock?

Recombinant PTP1B/PTPN1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant PTP1B/PTPN1 Monoclonal Antibody?

Recombinant PTP1B/PTPN1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant PTP1B/PTPN1 Monoclonal Antibody?

Estimated delivery time for Recombinant PTP1B/PTPN1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant PTP1B/PTPN1 Monoclonal Antibody?

The safety data sheet for Recombinant PTP1B/PTPN1 Monoclonal Antibody is available here: https://789.bio/eb/orQ7nnKq.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.