Recombinant Phospho-ERK1/2 (Thr202, Tyr204) Monoclonal Antibody

Specifications

Catalog number

AN300365L-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Abbreviation

MAPK3

UniProt

P27361

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues around Thr202, Tyr204 of Human Phospho-ERK1/2.

Target

ERT; PRKM; MAPK; P44ERK; p44-ERK; ERK; ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK; MAPK3; ERK 1; ERT 2; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; Insulin Stimulated MAP2 Kinase; Insulin-stimulated MAP2 kinase; MAP Kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK1; MGC20180; Microtubule Associated Protein 2 Kinase; Microtubule-associated protein 2 kinase; Mitogen Activated Protein Kinase 3; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 3; MK03; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; PRKM 3; Protein Kinase Mitogen Activated 3

Clonality

Monoclonal

Clone

11A1

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:20000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

41 kDa

Observed Molecular Weight

41 kDa

Isotype

IgG