Recombinant Phospho-MEK1/2 (Ser217, 2210) Monoclonal Antibody

Specifications

Catalog number

AN300366L-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Abbreviation

MAP2K1

UniProt

Q02750

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues around Ser218 and Ser222 of the Human MEK1

Target

MEK; MKK; CFC; MAPKK; PRKMK; MAP2K; CFC3; MAPKK1; MEK1; MKK1; PRKMK1; MAP2K1; Dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAPK/ERK kinase 1; MAPKK 1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MP2K1; Protein kinase mitogen activated; Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1)

Clonality

Monoclonal

Clone

11A4

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:2000-1:20000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

43 kDa

Isotype

IgG