Recombinant Phospho-VEGF Receptor 2 (Tyr1175) Monoclonal Antibody

Specifications

Catalog number

AN300385L-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Abbreviation

KDR

UniProt

P35968

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the residues around Tyr1175 of Human Phospho-VEGF Receptor 2

Target

Krd; VEGF Receptor; Fetal liver kinase; Protein-tyrosine kinase receptor flk; Vascular endothelial growth factor receptor; sVEGFR; VEGF R;6130401C; FLK; CD309; FLK1; VEGFR; VEGFR2; VEGF Receptor 2; KDR;6130401C07; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Krd-1; Ly73; Protein-tyrosine kinase receptor flk-1; sVEGFR-2; Vascular endothelial growth factor receptor 2; VEGF R2; VEGFR-2; KDR

Clonality

Monoclonal

Clone

11G9

Conjugation

Unconjugated

Applications

WB

Field of Research

Cardiovascular; Microbiology; Signal Transduction; Stem Cells; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:10000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

152 kDa

Observed Molecular Weight

280 kDa

Isotype

IgG