Recombinant Phospho-Src (Tyr530) Monoclonal Antibody

Specifications

Catalog number

AN300386L-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Abbreviation

SRC

UniProt

P12931

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the residues around

Target

THC; ASV; SRC1; THC6; c-SRC; p60-Src; SRC; pp60c-src; Proto-oncogene c-Src; Proto-oncogene tyrosine-protein kinase Src; Avian sarcoma virus; c SRC; CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA; cSrc; EC 2.7.10.2; Neuronal CSRC tyrosine specific protein kinase; Neuronal SRC; Oncogene SRC; OTTHUMP00000174476; OTTHUMP00000174477; p60 Src; p60Src; pp60c src; pp60csrc; Proto oncogene tyrosine protein kinase Src; Protooncogene SRC; Protooncogene SRC Rous sarcoma; SRC Oncogene; SRC proto oncogene non receptor tyrosine kinase; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC 1; Tyrosine protein kinase SRC1; v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog; V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) ; v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian

Clonality

Monoclonal

Clone

11G10

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:10000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60 kDa

Observed Molecular Weight

60 kDa

Isotype

IgG