Recombinant Carbonic Anhydrase II/Car2 Monoclonal Antibody

Specifications

Catalog number

AN300544P

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase II is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.

Abbreviation

CA2

UniProt

P00920

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant Mouse Carbonic Anhydrase II/CA2 protein

Target

Car; Car2; Ca2; AI131712; CAC; CAII; CA-II; Car-2; Ltw-5; Lvtw-5

Clonality

Monoclonal

Clone

4F4

Conjugation

Unconjugated

Applications

IHC-P

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG