Recombinant UCHL3 Monoclonal Antibody

Catalog number AN300584P

Discontinued

Price for AN300584P

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: AN300584P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase that belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer.
Abbreviation: UCHL3
UniProt: Q91Y78
Host: Rabbit
Reactivity: Rat
Immunogen: Recombinant Rat UCHL3 protein
Target: RGD; UCHL; rCG_37146; RGD1561196; Uchl3
Clonality: Monoclonal
Clone: 11B5
Conjugation: Unconjugated
Applications: WB; IHC-P; IP
Purification: Protein A
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC-P 1:100-1:500; IP 1-4 μL/mg of lysate
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 26 kDa
Observed Molecular Weight: 31 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant UCHL3 Monoclonal Antibody?

The catalog number for Recombinant UCHL3 Monoclonal Antibody is AN300584P.

What sizes are available for Recombinant UCHL3 Monoclonal Antibody?

Recombinant UCHL3 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant UCHL3 Monoclonal Antibody in stock?

Recombinant UCHL3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant UCHL3 Monoclonal Antibody?

Recombinant UCHL3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant UCHL3 Monoclonal Antibody?

Estimated delivery time for Recombinant UCHL3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant UCHL3 Monoclonal Antibody?

The safety data sheet for Recombinant UCHL3 Monoclonal Antibody is available here: https://789.bio/eb/6VsevrPd.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.