Recombinant BCAM/CD239 Monoclonal Antibody

Catalog number AN300587P

Price for AN300587P

Size / count 100 µL

Specifications

Catalog number: AN300587P
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The Lutheran (Lu) blood group and basal cell adhesion molecule (BCAM) antigens are both carried by 2 glycoprotein isoforms of the immunoglobulin superfamily representing receptors for the laminin alpha (5) chain. It is a transmembrane receptor with five immunoglobulin-like domains in its extracellular region, and is therefore classified as a member of the immunoglobulin (Ig) gene family. In addition to red blood cells, Lu/BCAM proteins are expressed in endothelial cells of vascular capillaries and in epithelial cells of several tissues. BCAM/LU has a wide tissue distribution with a predominant expression in the basal layer of the epithelium and the endothelium of blood vessel walls. As designated as CD239 recently, BCAM and LU share a significant sequence similarity with the CD146 (MUC18) and CD166, and themselves are adhesion molecules that bind laminin with high affinity. Laminins are found in all basement membranes and are involved in cell differentiation, adhesion, migration, and proliferation. BCAM is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. In addition, BCAM interacts with integrin in sickle red cells, and thus may potentially play a role in vaso-occlusive episodes.
Abbreviation: BCAM
UniProt: Q9ESS6
Host: Rabbit
Reactivity: Rat
Immunogen: Recombinant Rat BCAM/CD239 protein
Target: PVRL; PVRL2; Lu; Bcam
Clonality: Monoclonal
Clone: 11B10
Conjugation: Unconjugated
Applications: IHC-P
Purification: Protein A
Concentration: 1 mg/mL
Dilution: IHC-P 1:100-1:500
Buffer: 0.2 μm filtered solution in PBS
Shipping Conditions: Ice bag
Storage Conditions: This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant BCAM/CD239 Monoclonal Antibody?

The catalog number for Recombinant BCAM/CD239 Monoclonal Antibody is AN300587P.

What sizes are available for Recombinant BCAM/CD239 Monoclonal Antibody?

Recombinant BCAM/CD239 Monoclonal Antibody is available in the following size(s): 100 µL.

Is Recombinant BCAM/CD239 Monoclonal Antibody in stock?

Recombinant BCAM/CD239 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant BCAM/CD239 Monoclonal Antibody?

Recombinant BCAM/CD239 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant BCAM/CD239 Monoclonal Antibody?

Estimated delivery time for Recombinant BCAM/CD239 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant BCAM/CD239 Monoclonal Antibody?

The safety data sheet for Recombinant BCAM/CD239 Monoclonal Antibody is available here: https://789.bio/eb/MQd0Oj18.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.