Recombinant Bad Monoclonal Antibody

Specifications

Catalog number

AN300995L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Abbreviation

Bad

UniProt

Q92934

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Bad protein

Target

BCL2L; BBC; BAD; BBC2; BCL2L8; BBC6; AI325008; BBC 2; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl-2-binding component 6; Bcl2-L-8; Bcl-2-like protein 8; Bcl-XL/Bcl-2-associated death promoter; Proapoptotic BH3 Only Protein

Clonality

Monoclonal, Recombinant

Clone

11B12

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

18 kDa

Observed Molecular Weight

23 kDa

Isotype

IgG, κ