Recombinant EpCAM Monoclonal Antibody

Specifications

Catalog number

AN300999L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Abbreviation

EpCAM

UniProt

P16422

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human EpCAM protein

Target

M4S; MIC; M1S; DIAR; TROP; HNPCC; GA733; TACSTD; EGP; EPCAM; DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1; Ep-CAM; epithelial cell adhesion molecule; GA733-2; M1S2; MK-1; KSA; EGP40; TROP1;17 1A;323/A3;35-KD glycoprotein; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; chromosome 4; CO 17A; CO17 1A; CO17A; EGP 2; EGP2; Ep CAM; EpCAM1; Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) ; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; Epithelial glycoprotein 1; Epithelial glycoprotein 314; EpithelialGlycoprotein; GA733 1; GA733 2; gastrointestinal tumor-associated antigen 2; gp4; hEGP 2; hEGP314; Human epithelial glycoprotein 2; KS 1/4 antigen; KS 1/4 antigen.KSA; Ly74; Lymphocyte antigen 74; M1S 1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component; Membrane component chromosome 4 surface marker (35kD glycoprotein) ; MK 1; Protein 289A; surface marker; surface marker 1; TACD1; Tumor associated calcium signal transducer 1; Tumor associated calcium signal transducer 2 precursor; Tumor-associated calcium signal transducer 1

Clonality

Monoclonal, Recombinant

Clone

12B5

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Tags & Cell Markers

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

35 kDa

Observed Molecular Weight

40 kDa

Isotype

IgG, κ