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Product details

Recombinant XBP1 Monoclonal Antibody

Catalog number AN301006L-01

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Price for AN301006L-01

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Size / count 50 µL

Specifications

Catalog number
AN301006L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1) . The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1 (S), which is the functionally active transcription factor.
Abbreviation
XBP1
UniProt
P17861
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human XBP1 protein
Target
CBX; X-box-binding protein; Tax responsive element binding protein; Tax-responsive element-binding protein; XBP; XBP1; TREB-5; TREB5; XBP-1; XBP2; XBP1s; CBX1; Tax responsive element binding protein 5; Tax-responsive element-binding protein 5; X box binding protein 1; X box binding protein 2; X-box-binding protein 1; XBP 1
Clonality
Monoclonal, Recombinant
Clone
12B12
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
35 kDa,60 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant XBP1 Monoclonal Antibody?

The catalog number for Recombinant XBP1 Monoclonal Antibody is AN301006L.

What sizes are available for Recombinant XBP1 Monoclonal Antibody?

Recombinant XBP1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant XBP1 Monoclonal Antibody come in?

Recombinant XBP1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant XBP1 Monoclonal Antibody in stock?

Recombinant XBP1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant XBP1 Monoclonal Antibody?

Recombinant XBP1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant XBP1 Monoclonal Antibody?

Estimated delivery time for Recombinant XBP1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant XBP1 Monoclonal Antibody?

The safety data sheet for Recombinant XBP1 Monoclonal Antibody is available here: https://789.bio/eb/aSaPKQVS.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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