Recombinant PTEN Monoclonal Antibody

Catalog number AN301026L-01

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Price for AN301026L-01

Size / count 50 µL

Specifications

Catalog number: AN301026L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Phosphatase and tensin homolog (PTEN) Homo sapiens This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane.
Abbreviation: PTEN
UniProt: P60484
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Human PTEN protein
Target: CWS; GLM; TEP; MMAC;10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1; PTEN; PTENbeta;5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; MGC11227; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; Phosphatase and tensin like protein; Phosphatidylinositol 3; Phosphatidylinositol 3;4;5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Clonality: Monoclonal, Recombinant
Clone: 5A1
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cell Biology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Metabolism
Purification: Protein A
Concentration: 0.2 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:200-1:1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 47 kDa
Observed Molecular Weight: 56 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant PTEN Monoclonal Antibody?

The catalog number for Recombinant PTEN Monoclonal Antibody is AN301026L.

What sizes are available for Recombinant PTEN Monoclonal Antibody?

Recombinant PTEN Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant PTEN Monoclonal Antibody come in?

Recombinant PTEN Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant PTEN Monoclonal Antibody in stock?

Recombinant PTEN Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant PTEN Monoclonal Antibody?

Recombinant PTEN Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant PTEN Monoclonal Antibody?

Estimated delivery time for Recombinant PTEN Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant PTEN Monoclonal Antibody?

The safety data sheet for Recombinant PTEN Monoclonal Antibody is available here: https://789.bio/eb/hdETEVgY.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.