Recombinant Neurofilament heavy polypeptide Monoclonal Antibody

Specifications

Catalog number

AN301031L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Abbreviation

Neurofilament heavy polypeptide

UniProt

P12036

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Neurofilament heavy polypeptide protein

Target

KIAA; CMT2CC; NFH; NEFH; NF H; NF-H;200 kDa neurofilament protein; Neurofilament heavy polypeptide; Neurofilament heavy polypeptide 200kDa; Neurofilament triplet H protein; KIAA0845; Heavy Polypeptide 200kDa; Neurofilament; Neurofilament Heavy; NF-H

Clonality

Monoclonal, Recombinant

Clone

5A6

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Developmental Biology

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

110 kDa

Observed Molecular Weight

180-200 kDa

Isotype

IgG, κ