Recombinant Calreticulin Monoclonal Antibody

Catalog number AN301032L-01

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Price for AN301032L-01

Size / count 50 µL

Specifications

Catalog number: AN301032L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Calreticulin is a multifunctional protein that acts as a major Ca (2+) -binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.
Abbreviation: Calreticulin
UniProt: P27797
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Human Calreticulin protein
Target: CRP; ERp; endoplasmic reticulum resident protein; CaBP; CALR; CRT; HEL-S-99n; RO; SSA; cC1qR; CaBP3; calregulin; Calreticulin; calsequestrin-like protein; CRP55; endoplasmic reticulum resident protein 60; ERp60; CRTC; Autoantigen RO; CALR protein; calreticulin) ; Epididymis secretory sperm binding protein Li 99n; FLJ26680; grp60; HACBP; HEL S 99n; Sicca syndrome antigen A; Sicca syndrome antigen A (autoantigen Ro; Calregulin
Clonality: Monoclonal, Recombinant
Clone: 5A7
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Tags & Cell Markers; Signal Transduction
Purification: Protein A
Concentration: 0.2 mg/mL
Dilution: IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 48 kDa
Observed Molecular Weight: 55 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Calreticulin Monoclonal Antibody?

The catalog number for Recombinant Calreticulin Monoclonal Antibody is AN301032L.

What sizes are available for Recombinant Calreticulin Monoclonal Antibody?

Recombinant Calreticulin Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Calreticulin Monoclonal Antibody come in?

Recombinant Calreticulin Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Calreticulin Monoclonal Antibody in stock?

Recombinant Calreticulin Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Calreticulin Monoclonal Antibody?

Recombinant Calreticulin Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Calreticulin Monoclonal Antibody?

Estimated delivery time for Recombinant Calreticulin Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Calreticulin Monoclonal Antibody?

The safety data sheet for Recombinant Calreticulin Monoclonal Antibody is available here: https://789.bio/eb/PevrkYxO.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.