Recombinant DRP1 Monoclonal Antibody

Specifications

Catalog number

AN301080L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) . Alternative splicing results in multiple transcript variants encoding different isoforms.

Abbreviation

DRP1

UniProt

O00429

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human DRP1 protein

Target

DRP; DLP; DNM1L; DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; Dnm1p/Vps1p-like protein (DVLP) ; dynamin 1 like; Dynamin family member proline-rich carboxyl-terminal domain less (Dymple) ; Dynamin-1-like protein; Dynamin-like protein; DLP1; DRP1; DVLP; DYMPLE; dynamin 1 like; EMPF; EMPF1; HDYNIV; Dnm1p/Vps1p-like protein; dnml1; Dynamin family member proline-rich carboxyl-terminal domain less; Dynamin like protein; Dynamin related protein 1; Dynamin-like protein 4; Dynamin-like protein IV; Dynamin-related protein 1; DYNIV 11; FLJ41912; VPS1

Clonality

Monoclonal, Recombinant

Clone

2C6

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Cell Biology; Signal Transduction; Metabolism; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1000; WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

83 kDa

Observed Molecular Weight

83 kDa

Isotype

IgG, κ