Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody

Catalog number AN301427L-01

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Price for AN301427L-01

Size / count 50 µL

Specifications

Catalog number: AN301427L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B) . Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor such as ACVR1B. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail.
Abbreviation: Activin A Receptor Type IB/ALK-4
UniProt: P36896
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Recombinant human Activin A Receptor Type IB/ALK-4 fragment
Target: SKR; Activin Receptor-Like Kinase; Serine/Threonine-Protein Kinase Receptor R; ACVRLK; ALK; ACVR1B; ACTRIB; ACVRLK4; ALK4; SKR2; Activin Receptor Type IB; Activin Receptor Type-1B; Activin Receptor-Like Kinase 4; ACTR-IB; ALK-4; Serine/Threonine-Protein Kinase Receptor R2
Clonality: Monoclonal, Recombinant
Clone: A122
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Signal Transduction; Stem Cells
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IF 1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 52 kDa
Observed Molecular Weight: 55 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody?

The catalog number for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is AN301427L.

What sizes are available for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody?

Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody come in?

Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody in stock?

Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody?

Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody?

Estimated delivery time for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody?

The safety data sheet for Recombinant Activin A Receptor Type IB/ALK-4 Monoclonal Antibody is available here: https://789.bio/eb/OJChiqwJ.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.