Recombinant alpha smooth muscle Actin Monoclonal Antibody

Specifications

Catalog number

AN301435L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Alpha smooth muscle actin encoded by the ACTA2 gene is a key protein in the highly conserved actin family, which plays a crucial role in cell motility, structure and integrity. This isoform is predominantly expressed in vascular smooth muscle cells, where it is essential for maintaining the structure and function of blood vessels and other smooth muscle tissues. Mutations in ACTA2 are linked to various vascular disorders, including familial thoracic aortic aneurysms and dissections (TAAD) and multisystemic smooth muscle dysfunction syndrome.

Abbreviation

Alpha smooth muscle Actin

UniProt

P62736

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human alpha smooth muscle Actin fragment

Target

AAT; GIG; MYMY; Growth inhibiting gene; AAT6; ACTSA; MYMY5; ACTA2; actin; a actin; Actin aortic smooth muscle; Growth inhibiting gene 46; ACTVS; GIG46; Actin alpha 2 smooth muscle aorta; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; alpha sma; Alpha-actin-2; aortic smooth muscle; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; α-SMA; a actin; AAT6; ACTA; ACTA2; Actin aortic smooth muscle; Actin; ACTSA; ACTVS; GIG46; Growth inhibiting gene 46; MYMY5

Clonality

Monoclonal, Recombinant

Clone

A130

Conjugation

Unconjugated

Applications

WB; IHC; IF; FCM; IP

Field of Research

Signal Transduction; Stem Cells; Cardiovascular; Developmental Biology

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:1000-1:5000; IF 1:50; FCM 1:50-1:100; IP 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa

Observed Molecular Weight

42 kDa

Isotype

IgG, κ